Phenylalanine is the vital alpha amino acid that works to maintain adequate levels of the monoamine neurotransmitter in the brain, which in turn maintains a balanced mood. A deficiency in phenylalanine causes depression, mental confusion, decreased alertness, loss of appetite and memory impairment. Phenylalanine is found mainly in three types of L-Phenylalanine, DL-Phenylalanine and D-Phenylalanine. L-phenylalanine is the natural amino acid found in proteins, while D-phenylalanine is the synthesized form of phenylalanine, produced in the laboratory. DL-phenylalanine is a synthetic product made with half D-phenylalanine and half L-phenylalanine.

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L-Phenylalanine is the vital amino acid which is also the only form of phenylalanine found in protein. The main dietary sources of L-phenylalanine are meat, fish, cheese, milk and eggs. DL-Phenylalanine and L-Phenylalanine are commonly used for the treatment of depression, chronic pain, Attention Deficit Hyperactivity Disorder (ADHD), and a skin condition called vitiligo.

The main function of phenylalanine is the production of tyrosine, which is then converted into 3 major neurotransmitters, namely norepinephrine, epinephrine and L-dopa. Since some antidepressants work by increasing norepinephrine levels, various forms of phenylalanine have been considered a potential treatment for depression. In addition, D-phenylalanine has been shown to be effective in the treatment of chronic pain.

Global Phenylalanine Market Drivers

Rising prevalence of depression and anxiety leads to massive consumption of antidepressants, which in turn is expected to drive the growth of the global market. phenylalanine market over the forecast period. For example, according to 2017 data from the World Health Organization (WHO), approximately 300 million people of all ages suffer from depression worldwide, and more than 800,000 people die of suicide due to depression and anxiety disorders as the main cause. Additionally, according to the National Institute of Mental Health (NIMH), approximately 10.3 million adults in the United States (4.3% of total American adults) aged 18 and older have suffered from at minus one massive depressive episode with severe impairment, in 2016. In addition, according to the same source, the incidence of the main cases of depression was high in adult women (8.5%) than in men (4.8%) . In addition, the incidence of adults with a massive depressive episode was higher among those aged 18 to 25 years (10.9%). The association (NIMH) even mentions that the disorders are extremely treatable which is expected to propel the growth of the global phenylalanine market during the forecast period.

Furthermore, the high prevalence of chronic pain is expected to drive the growth of the global phenylalanine market during the forecast period. For example, in 2011, according to the American Academy of Pain Medicine (AAPM), more than 1.8 billion people suffered from chronic pain. Additionally, the National Institutes of Health (NIH) estimates that 10% of the American population suffers from chronic pain. According to the study published by the British Medical Journal in 2016, over 33% of the population in the UK suffers from chronic pain. In addition, according to NIH estimates released in 2015 by the American Pain Society, more than 50 million people in the United States have suffered from chronic pain.

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In addition, the increasing prevalence of chronic diseases and pain including cancer and others is expected to drive the growth of the global phenylalanine market during the forecast period. For example, in 2018, according to the National Cancer Institute, more than 1,735,350 new cases of cancer are expected to be registered in the United States, while 609,640 people are expected to die from the disease.

Global Phenylalanine Market Restrictions

The side effects associated with phenylalanine are expected to restrain the growth of the global phenylalanine market during the forecast period. Phenylalanine should be avoided by people with certain inherited disorders, including phenylketonuria (PKU), in which the body builds up excess phenylalanine. People with phenylketonuria can develop high blood pressure, mental retardation, stroke, and various other serious health problems if they take phenylalanine.

Global Phenylalanine Market – Regional analysis

On the basis of geography, the global phenylalanine market is divided into North America, Europe, Latin America, Middle East, Africa, and Asia-Pacific. The increasing prevalence of cancer and the increasing number of trauma cases around the world are expected to drive the demand for the management of the pain associated with it. The North America region is expected to register robust growth during the forecast period. According to statistics released by the Centers for Disease Control and Prevention (CDC) in 2014, approximately 41 million emergency room visits are recorded each year for trauma in the United States.

In addition, developed economies including the United States, Germany and the United Kingdom are experiencing high adoption rates due to better health care facilities and easy access to depression medications in the world. the countries. According to the American Academy of Pain Medicine, each year over 100 million people suffer from chronic pain, over 25.8 million have diabetes, over 16.3 million have coronary heart disease, and over 11.9 million cancer in the United States. the forecast period.

Increase R&D initiatives by several non-governmental and governmental organizations, including the National Institutes of Health (NIH) Brain Research through Advancing Innovative Neurotechnologies (BRAIN) which aims to better understand the human brain and to exploit it in several therapeutic applications, as effective pain management, is expected to create a conducive environment for the growth of the global phenylalanine market in these regions.

Global Phenylalanine Market – Competitor

The major players operating in the global phenylalanine market are Amazing Nutrition, NutraMarks, Inc., LiftMode (Synaptent LLC), NOW Foods, Shijiazhuang Jirong Pharmaceutical Co., Ltd. and healthvit.

Global Phenylalanine Market Taxonomy

Based on type

• D-Phenylalanine
• L-phenylalanine
• DL-phenylalanine

Based on the application:

• Chronic pain
• Depression
• Vitiligo

Based on distribution channel:

• Retail pharmacy
• Hospital pharmacy
• Online pharmacy

Based on region

• North America
• Europe
• Latin America
• Asia Pacific
• Africa
• Middle East

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