TUESDAY, Aug. 16, 2022 (HealthDay News) — Gout is more common among self-reported black versus white adults, but those differences are attenuated after full adjustment for all risk factors, according to a study published online Aug. 15, 2022. august in Open JAMA Network.

Natalie McCormick, Ph.D., of Massachusetts General Hospital in Boston, and colleagues examined gender-specific factors driving disparities between black and white adults in the contemporary prevalence of gout in the general population in the states. United States using data from the National Health and Nutrition Examination Survey from 2007 to 2016. Data was included for 18,693 participants, including 3,304 black women, 6,195 white women, 3,085 black men, and 6,109 white men.

The researchers found that the age-standardized prevalence of gout was 3.5 and 2.0% in black and white women, respectively, and 7.0 and 5.4%, respectively, in men. blacks and whites (age-adjusted odds ratios, 1.81 [95 percent confidence interval, 1.29 to 2.53] and 1.26 [95 percent confidence interval, 1.02 to 1.55], respectively). After adjusting for poverty, diet, body mass index and chronic kidney disease (CRI) in women and for diet and CRI in men, the associations attenuate and become zero after adjustment for all risk factors (age-adjusted odds ratios, 1.05 [95 percent confidence interval, 0.67 to 1.65) and 1.05 [95 percent confidence interval, 0.80 to 1.35] in women and men, respectively). Endpoint results for hyperuricemia were similar.

“Culturally informed interventions designed to address adiposity and kidney disease and improve diet quality while recognizing the role of poverty in gout among women could help reduce these disparities,” the authors write.

Several authors disclosed financial ties to the biopharmaceutical industry.